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Sodium Dodecyl Sulfate

Cas No.:151-21-3
Appearance:White Powder Form
Molecular Formula:CH3(CH2)nOSO3Na, n=11,13
ProductionCapacity:

Detailed information

Sodium Dodecyl Sulfate Molecular Formula:
CH3(CH2)nOSO3Na, n=11,13
Sodium Dodecyl Sulfate Structure

Sodium Dodecyl Sulfate Feature:

  1. Good Emulsifying, foaming, osmosis, detergency and dispersing performances.
  2. Dissolves in the water easily.
  3. Compatibility with anion and non-ionic.
  4. Fast biodegradability

Sodium Dodecyl Sulfate Application:

  1. Detergency: tooth paste, shampoo, cosmetic, detergent and so on
  2. Construction: plasterboard, additive of concrete, coating and so on
  3. Pharmaceutical: Medicine, pesticide and so on
  4. Leather: leather soft agent, wool cleaning agent and so on
  5. Paper making: penetrant, flocculating agent, deinking agent and so on
  6. Auxiliaries: textile auxiliaries, plastic auxiliaries and so on
  7. Fire fighting: oil well fire fighting, fire fighting device and so on
  8. Mineral choosing: mine flotation, coal water mixture and so on
  9. Rubber latex
  10. PVC Paste Resin
  11. Electrolyzation of Manganese Dioxide

Sodium Dodecyl Sulfate Package

  1. Powder and needle form products in craft-paper bags or woven bags, 20 Kg net weight.
  2. Liquid form products in plastic barrels, 200 Kg net weight.

Sodium Dodecyl Sulfate Storage

  1. Powder and needle form products, store in a cool, dry place. Avoid moisture and heat.

Liquid products, no excess press.

Sodium dodecyl sulfate Production

Sodium dodecyl sulfate (SDS or NaDS), sodium laurilsulfate or sodium lauryl sulfate (SLS) is an organic compound with the formula CH3(CH2)11SO4Na. Sodium dodecyl sulfate is an anionic surfactant used in many cleaning and hygiene products. The salt is of an organosulfate consisting of a 12-carbon tail attached to a sulfate group, giving the material the amphiphilic properties required of a detergent. Derived from inexpensive coconut and palm oils, Sodium dodecyl sulfate is a common component of many domestic cleaning products.

Sodium dodecyl sulfate is synthesized by treating lauryl alcohol with sulfur trioxide gas, oleum, or chlorosulfuric acid to produce hydrogen lauryl sulfate. The industrially practiced method typically uses sulfur trioxide gas. The resulting product is then neutralized through the addition of sodium hydroxide or sodium carbonate. Lauryl alcohol is in turn usually derived from either coconut or palm kernel oil by hydrolysis, which liberates their fatty acids, followed by hydrogenation.
Due to this synthesis method, commercial samples of Sodium dodecyl sulfate are often a mixture of other alkyl sulfates, dodecyl sulfate being the main component.
Sodium dodecyl sulfate is available commercially in powder and pellet forms. It seems the pellet form dissolves faster than the powder form in water.

Sodium dodecyl sulfate Cleaning and hygiene

Sodium dodecyl sulfate is mainly used in detergents for laundry with many cleaning applications. Sodium dodecyl sulfate is a highly effective surfactant and is used in any task requiring the removal of oily stains and residues. For example, Sodium dodecyl sulfate is found in higher concentrations with industrial products including engine degreasers, floor cleaners, and car wash soaps. Sodium dodecyl sulfate is found in toothpastes, shampoos, shaving creams, and bubble bath formulations in part for its thickening effect and its ability to create a lather. Pepsodent toothpaste at one time used the name "Irium" for its sodium lauryl sulfate ingredient.

Sodium dodecyl sulfate Laboratory applications

Sodium dodecyl sulfate can be used to aid in lysing cells during DNA extraction and for unraveling proteins in Sodium dodecyl sulfate-PAGE. Sodium lauryl sulfate, in science referred to as sodium dodecyl sulfate (Sodium dodecyl sulfate) or Duponol, is commonly used in preparing proteins for electrophoresis in the Sodium dodecyl sulfate-PAGE technique. This compound works by disrupting non-covalent bonds in the proteins, denaturing them, and causing the molecules to lose their native shape (conformation).

This new negative charge is significantly greater than the original charge of that protein. The electrostatic repulsion that is created by binding of Sodium dodecyl sulfate causes proteins to unfold into a rod-like shape thereby eliminating differences in shape as a factor for separation in the gel.

Sodium lauryl sulfate is probably the most researched anionic surfactant compound. Like all detergent surfactants, sodium lauryl sulfate removes oils from the skin, and can cause skin and eye irritation. The critical micelle concentration (CMC) in pure water at 25 °C is 8.2 mM, and the aggregation number at this concentration is usually considered to be about 62. The micelle ionization fraction (α) is around 0.3 (or 30%).

Aqueous solutions of Sodium dodecyl sulfate are also popular for dispersing or suspending nanotubes, such as carbon nanotubes (CNTs). However, sodium dodecylbenzene sulfonate (NaDDBS) and Triton X-100 are reported to be better dispersants of single walled carbon nanotubes.

Sodium lauryl sulfate is also used in the analysis of hemoglobin. The hydrophobic group of SLS acts upon the globin subunit, causing a conformational change. The hydrophilic group of SLS then binds with the oxidized iron subunit, producing a stable reaction product which can then be analyzed, giving a hemoglobin value which is used as part of a complete blood count.

Sodium dodecyl sulfate is also used to clear brain tissue, by removing lipids responsible for light scattering. Biological tissues treated by sodium dodecyl sulfate are rendered quasi-transparent in optical microscopy, enabling to see through them.

Sodium dodecyl sulfate Niche uses

Sodium dodecyl sulfate Biocide

SDS represents a potentially effective topical microbicide, which can also inhibit and possibly prevent infection by various enveloped and non-enveloped viruses such as the Herpes simplex viruses, HIV, and the Semliki Forest Virus.

Sodium dodecyl sulfate Shark repellent

Evidence suggests that surfactants such as sodium lauryl sulfate can act as a shark repellent at concentrations on the order of 100 parts per million. However, this does not meet the desired "cloud" deterrence level of 0.1 parts per million.

Sodium dodecyl sulfate Pesticide

Sodium dodecyl sulfate is an EPA approved inert ingredient for pesticide formulations. Sodium dodecyl sulfate is also considered a Minimum Risk Pesticides Exempted from FIFRA Registration by the EPA under 40 CFR 152.25(f).

Sodium dodecyl sulfate Food additive

Sodium dodecyl sulfate is used under the name sodium lauryl sulfate in some food products as an emulsifying agent and whipping aid. Sodium dodecyl sulfate is considered generally recognized as safe (GRAS) for food use when used according to the guidelines published in 21 CFR 172.822.

Sodium dodecyl sulfate Carcinogenicity

Sodium dodecyl sulfate is not carcinogenic when either applied directly to skin or consumed. A review of the scientific literature stated "SLS [Sodium dodecyl sulfate] was negative in an Ames (bacterial mutation) test, a gene mutation and sister chromatid exchange test in mammalian cells, as well as in an in vivo micronucleus assay in mice. The negative results from in vitro and in vivo studies indicate Sodium dodecyl sulfate does not interact with DNA." The same review also stated "In the only carcinogenicity study available, Sodium dodecyl sulfate was not carcinogenic in Beagle dogs, though the short study duration and limited details provided limit the significance that can be attached to the data."

Sodium dodecyl sulfate Sensitivity

Sodium dodecyl sulfate has been shown to irritate the skin of the face, with prolonged and constant exposure (more than an hour) in young adults. Sodium dodecyl sulfate may worsen skin problems in individuals with chronic skin hypersensitivity, with some people being affected more than others. In animal studies Sodium dodecyl sulfate appears to cause skin and eye irritation.

Sodium dodecyl sulfate can contact the face from aerosolized dust when using Sodium dodecyl sulfate in its powder form in the laboratory. To prevent contact with face and eyes, a dust-free “pellet” form of Sodium dodecyl sulfate is available which essentially eliminates Sodium dodecyl sulfate dust inhalation and contact with the face.

Sodium dodecyl sulfate Aphthous ulcers

There have been several studies on how Sodium dodecyl sulfate in toothpaste affects the recurrence of aphthous ulcers, commonly referred to in some countries as canker sores or white sores. The results of these studies have been inconsistent.

In 1994, a preliminary crossover study showed patients had a significantly higher number of aphthous ulcers after using SLS-containing toothpaste, compared with an SLS-free toothpaste. A follow-up double-blind crossover study in 1996 further supported these results, as did a separate study in 1997.

However, a double-blind crossover study published in 1999 failed to find any statistically significant difference. A double-blind crossover study in 2012 also failed to find a significant difference in number of ulcers, but did find a significant difference in ulcer duration and pain scores. According to the 2012 study, patients using an SLS-free toothpaste experienced faster healing of ulcers and less ulcer-related pain on average than patients using SLS-containing toothpaste.

Sodium Dodecyl Sulfate Standard:GB/T15963-2008

Item

Specification

Appearance

White Powder Form

White Needle Form

Clear, light yellow Liquid

General


For Plasterboard

Active ingredient (%)

≥92

≥93

≥95

≥92

≥93

≥95

≥31

≥32

≥35

Petroleum ether soluble substances (%)

≤1.5

≤1.5

≤1.5

≤1.5

≤1.5

≤1.5

≤0.3

≤1.5

≤1.5

Inorganic salts (NaCl+Na2SO4) (%)



≤5.5

≤4.5

≤2.5

≤4.5

≤3.5

≤2.5

≤0.5

≤2.0

≤2.0

Water (%)

≤2.5

≤2.5

≤2.5

≤3.5

≤3.5

≤3.0

-

-

-

pH (1% aq. solution)

7.5~9.5

7.5~9.5

7.5~9.5

7.5~9.5

7.5~9.5

7.5~9.5

7.5~9.5

7.5~9.5

7.5~9.5

Whiteness (WG)

≥90

≥90

≥90

≥90

≥90

≥90

-

-

-

Hazen color

-

-

-

-

-

-

≤70

≤50

≤50

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis

A rapid and convenient method for peptide mapping of proteins has been developed. The technique, which is especially suitable for analysis of proteins that have been isolated from gels containg sodium dodecyl sulfate, involves partial enzymatic proteolysis in the presence of sodium dodecyl sulfate and analysis of the cleavage products by polyacrylamide gel electrophoresis. The pattern of peptide fragments produced is characteristic of the protein substrate and the proteolytic enzyme and is highly reproducible. Several common proteases have been used including chymotrypsin, Staphylococcus aureus protease, and papain.

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

A discontinuous sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) system for the separation of proteins in the range from 1 to 100 kDa is described. Tricine, used as the trailing ion, allows a resolution of small proteins at lower acrylamide concentrations than in glycine-SDS-PAGE systems. A superior resolution of proteins, especially in the range between 5 and 20 kDa, is achieved without the necessity to use urea. Proteins above 30 kDa are already destacked within the sample gel. Thus a smooth passage of these proteins from sample to separating gel is warranted and overloading effects are reduced. This is of special importance when large amounts of protein are to be loaded onto preparative gels. The omission of glycine and urea prevents disturbances which might occur in the course of subsequent amino acid sequencing.


Sodium dodecyl sulfate images


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Sodium dodecyl sulfate images

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